Abstract : Polymeric nanoparticles (PNPs) are characterized as particulate dispersions or solid particles with a size in the range of 10-1000nm. There has been great scientific interest in the area of drug delivery, using particle delivery methods as carriers for small and large molecules. Particulate systems such as nanoparticles have been employed as a physical technique to alter and improve the pharmacokinetic and pharmacodynamic aspects of numerous types of medicinal molecules. Polymeric nanoparticles have been intensively explored as particulate carriers in in pharmaceutical and medical, industries because they show promise as drug delivery systems as a result of their controlled and sustained release capabilities, subcellular size, and biocompatibility with tissue and cells. Several methods to manufacture polymeric nanoparticles have been established and these strategies are classed according to whether particle creation needs a polymerization reaction or whether nanoparticles form directly from a macromolecule or premade polymer.
