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AIM: TO SYNTHESIZE CHALCONE FROM BENZALDEHYDE. RECORD MELTING POINT AND YIELD OF PRODUCT    

Authors : Dr. KAPIL KUMAR; Prof. (Dr.) ANUPAMA DIWAN

Publishing Date : 2022

DOI : https://doi.org/10.52458/9789391842697.2022.eb.grf.asu.ch-18

ISBN : 978-93-91842-69-7

Pages : 105

Chapter id : ASU/GRF/EB/AEHFPOC/2022/Ch-18

Abstract : Claisen-Schmidt condensation defined when benzaldehyde derivatives condensed with alkyl/aryl ketone in basic medium to afford ?, ?-unsaturated ketone. It follows cross aldol condensation type mechanism where intermediate is aldol which dehydrate in presence of acid/alkali to afford final unsaturated ketone which is known as “chalcone”. Generally, polar solvents favour the reaction kinetics to afford product in excellent yield.

Keywords : bacteria, viruses, inflammation, diabetes, CNS disorders, leishmania.

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